New Study Shows Salvia’s Anti-inflammatory effects

September 9, 2012

September 9, 2012New Study Shows Salvia Exerts Potent Anti-inflammatory Effects

Recent research has shed light on some fascinating properties of the main active ingredient in Salvia divinorum, Salvinorin A. This so called ‘non-nitrogenous kappa opioid receptor (KOR) agonist’ has been shown to reduce acute pain and to exert potent antinflammatory effects.

From the original article:

This study assesses the effects and the mode of action of SA on formalin-induced persistent pain in mice. Specifically, the SA effects on long-term behavioural dysfunctions and changes in neuronal activity occurring at spinal level, after single peripheral formalin injection, have been investigated.

Moreover, the involvement of microglial and glial cells in formalin-induced chronic pain condition and in SA-mediated effects has been evaluated.